The Wednesday Afternoon Lectures
1999-2000

The National Institutes of Health
Office of the Director

All Lectures are in Masur Auditorium, Bldg. 10, at 3:00 p.m.(exceptions are marked with an * below). The lectures may be accessed from personal computers via NIH's MBONE and are available on videotape at the NIH Library, Bldg. 10, approximately one week after the lecture date. Following the lectures are informal receptions featuring poster displays by winners of the Fellows Awards for Research Excellence (FARE). CME credit available** For further information or special accomodations, please contact: Ms. Hilda Madine.


September 15
Wolfram Schultz, M.D.
Professor and Chair of Neurophysiology
University of Fribourg
Fribourg, Switzerland
REWARD PROCESSING IN PRIMATE BASAL GANGLIA AND FRONTAL CORTEX
Hosted by Integrative Neuroscience IG (Sponsor: NINDS)

September 22
Vilayanur Ramachandran,M.D., Ph.D.
CANCELLED!

September 29
The George Khoury Lecture
Robert Tjian, Ph.D.
Professor of Molecular and Cell Biology
Investigator, HHMI, University of California, Berkeley
THE BIOCHEMISTRY OF EUKARYOTIC TRANSCRIPTION:
MORE SURPRISES AND COMPLEXITIES
Hosted by: Transcription Factors, Molecular Biology, and Genetics Interest Groups (Sponsor: NCI)

October 6: RESEARCH FESTIVAL: No Lecture

October 13
Virginia Zakian, Ph.D.
Professor, Dept. of Molecular Biology,
Princeton University
A TALE OF TWO HELICASES: THE SACCHAROMYCES
Pif1p AND Rrm3p HELICASES HAVE ANTAGONISTIC
EFFECTS ON REPLICATION OF BOTH TELOMERIC
AND RIBOSOMAL DNA
Hosted by: Development IG and Women Scientist Advisors (Sponsor: NICHD)

October 20
DeWitt Stetten, Jr. Lecture
James Spudich, Ph.D.
Stanford University School of Medincine
SINGLE-MOLECULE BIOMECHANICS AND THE
MYOSIN FAMILY OF MOLECULAR MOTORS
Hosted by: NIGMS and the Motility IG)
(Sponsor: NIMH)

*Special Thursday Lecture
October 28
Tim Mitchison, Ph.D., F.R.S.
Hasib Sabbagh Professor of Cell Biology,
Harvard Medical School, Boston
BIOCHEMICAL AND SMALL MOLECULE APPROACHES
TO DISSECTING MITOSIS
HOST: Cell Biology IG, host)
(Sponsor: NICHD)

*Special Tuesday Lecture
November 2
Leland Hartwell, Ph.D.
Director, F. Hutchinson Cancer Res. Cntr.
STUDYING THE FUNDAMENTALS
OF CANCER IN YEAST
Hosted by NIH Fellows)
(Sponsor: NCI)

November 3
NIH Director's Astute Clinician Lecture
Allen Steere, Jr., Ph.D.
Natalie V and Milton O Zuckerman Professor of Immunology,
Tufts Univ. School of Medicine
THE ELUCIDATION OF LYME ARTHRITIS
Hosted by the Clinical Center, and Office of the Director, OD

*Special Starting Time: 2:45 p.m.
November 10
Percy L Julian Centennial Lecture
Franklyn Prendergast, M.D., Ph.D.
Edmond and Marion Guggenheim Professor of Biochemistry and Molecular Biology, and Director, Mayo Clinic Cancer Center, Mayo Clinic and Foundation
ELEGANT PHOTOPHYSICS IN THE GREEN FLUORESCENT PROTEIN
Introduction to the Life of Percy Julian by Bernard Witkop, NIDDK Scientist Emeritus
Hosted by Chemistry IG, Black Scientists' Association
(Sponsor: NIDDK)

November 17
3rd James Shannon Lecture
Purnell Choppin, M.D.
President, HHMI
A ROLE FOR PRIVATE SUPPORT OF BIOMEDICAL RESEARCH
Hosted by the NIH Alumni Association
(Sponsor: NIAID)

November 24: Thanksgiving Break

December 1
Shirley Tilghman, Ph.D.
Howard A. Prior Professor of Life Sciences, Princeton
THE MECHANISM AND FUNCTION OF GENOMIC IMPRINTING IN MAMMALS
Hosted by Genetics and Clinical Research Interest Groups
(Sponsor: NIMH)

December 8
NIH Director's Lecture
Patrick Brown, M.D., Ph.D.
Associate Professor of Biochemistry, Stanford Univ. School of Medicine
THE LIVING GENOME
Host: NHGRI

December 15
Stephen Harrison, Ph.D.
Higgins Professor of Biochemistry and Director,
Center for Structural Biology, Harvard Medical School
VIRUSES AS MOLECULAR MACHINES
Hosted by Structural Biology IG
(Sponsored by NCBI)

December 22-January 5: Winter Break

January 12, 2000
Jeffrey Friedman , M.D., Ph.D.
Professor, Laboratory of Molecular Genetics
Investigator, HHMI, The Rockefeller University
LEPTIN AND THE NEURAL CIRCUIT
REGULATING BODY WEIGHT
Hosted by Genetics Interest Group
(Sponsored by NIDDK)

January 19
Antonio Lanzavecchia, M.D.
Director, Institute for Research in Biomedicine
Bellinzona, Switzerland
FROM SYNAPSES TO IMMUNOLOGICAL MEMORY
Hosted by the Immunology IG and Fogarty International Center
(Sponsored by NIA)

January 26
Snowed Out!
Rescheduled below!
Barry Bloom, Ph.D.

Feb. 2
NIH Mider Lecture
Bob Balaban,
Chief, Laboratory of Cardiac Energetics, NHLBI
DOMESTICATION OF THE MITOCHONDRION
FOR CELLULAR ENERGY CONVERSION
Hosted by NHLBI

Feb 9
Marc Tessier-Lavigne, Ph.D
Professior, Departments of Anatomy
and Biochemistry and Biophysics; Investigator HHMI, UCSF
WIRING THE BRAIN: MOLECULAR MECHANISMS
OF AXON GUIDANCE IN VERTEBRATES
hosted by Synaptic Plasticity IG
(sponsor: NINDS)

Feb. 16
Joseph Schlessinger , Ph.D
Chairman, Department of Pharmacology;
Director, Skirball Institute of Biomolecular Medicine,
Milton and Helen Kimmelman Professor of Pharmacology, NYU
CELLULAR SIGNALLING BY TYROSINE PHOSPHORYLATION
Hosted by Diabetes and Cell Biology Igs
Sponsor: NIDDK

Feb. 23
David L. Nelson,Ph.D
Professor, Department of Molecular and Human Genetics,
Baylor College of Medicine, Houston
THE HUMAN AS A MODEL SYSTEM IN GENETICS:
EXAMPLES FROM FRAGILE X SYNDROME AND INCONTINENTIA PIGMENTI
Hosted by Genetics IG (Sponsor: NIAAA)

Mar. 1
Gunter Blobel, M.D. Ph.D
John D. Rockefeller, Jr. Professor of Cell Biology,
Investigator, HHMI, Rockefeller University;
1999 Nobel Laureate in Physiology or Medicine
TRAFFIC INTO AND OUT OF THE NUCLEUS
Hosted by RNA club, Molecular Biology IGs
(Sponsor: NEI)

Mar 8
John Gearhart, Ph.D.
Professor and Director of Developmental Genetics,
Department of Obstetrics and Gynecology,
Schools of Medicine and Public Health, Johns Hopkins
HUMAN PLURIPOTENTIAL STEM CELLS
Hosted by the NIH Fellows (sponsor: NIDCR)

Mar 15
Gary Gibson, Ph.D.
Professor of Neuroscience, Weill Medical College of Cornell University
at Burke Medical Research Institute, NY
OXIDATIVE PROCESSES AND SIGNAL TRANSDUCTION
IN ALZHEIMER'S DISEASE:
INSIGHTS FROM BRAINS, PERIPHERAL CELLS, AND ANIMAL MODELS
Co-Hosted by Mitochondria Interest Group and Clinical Research IG)(Sponsor: NIDA)

Mar 22
Helen Blau, PH.D.
Donald E. and Delia B. Baxter Professor and
Chair, Department of Molecular Pharmacology,
Director, Gene Therapy Technology, Stanford
RESEARCH ADVANCES AND CLINICAL AND PUBLIC HEALTH IMPLICATIONS OF GENETIC THERAPY
Hosted by Developmental Biology IG and the WSAs (Sponsor: NIA)

Mar 29
Wolfgang Baumeister, Ph.D.
Professor, Max Planck Institute for Structural Biochemistry,
Martinsried, Germany
THE PROTEASOME: STRUCTURAL BASIS OF ITS FUNCTIONAL REPERTOIRE
Hosted by the Structural Biology IG and the Fogarty International Center (Sponsor: NEI)

April 5
Lucy Shapiro, Ph.D.
Ludwig Professor of Cancer Research,
Stanford University School of Medicine
PROTEIN LOCALIZATION AND CELL DIFFERENTIATION DURING THE CELL CYCLE Hosted by the Lambda Lunch and Molec. Biol. IGs (Sponsor: NICHD)

Apr 12
Robert S. Gordon Lecture in Epidemiology
Steven Cummings, M.D. FACP
Professor of Medicine and Epidemiology and Biostatistics;
Assistant Dean for Clinical Research, School of Medicine, UCSF
NEW TECHNOLOGY AND A TWO-EDGED SWORD: HOW BONE DENSITOMETRY HAS REVOLUTIONIZED AND IMPEDED THE UNDERSTANDING AND PREVENTION OF OSTEOPOROTIC FRACTURES
Hosted by the Epidemiology and Clinical Trials IG (Sponsor: NCI-DCE)

Apr 19
Caroline Damsky, Ph.D.
Professor and Vice Chair, Department of Stomatology
School of Dentistry, UCSF
A FIBRONECTIN-FAK SIGNALING AXIS: HOW SPECIAL IS IT?
Hosted by the WSAs, Cell Matrix, and Cell Biology IGs (Sponsor: NIDCR)

April 26
Margaret Pittman Lecture
Janet Rowley, M.D., D.Sc.
Blum-Riese Distinguished Service Professor, Department of Medicine,
and Department of Molecular Genetics and Cell Biology and Human Genetics
Univ. of Chicago
CANCER CYTOGENETICS: IS IT PASSE?
Host: NHGRI

May 3
Dyer Lecture
Rescheduled!
Barry Bloom, Ph.D.
Dean of the Faculty and Professor,
Immunology and Infectious Diseases,
Harvard School of Public Health
A VIEW OF PUBLIC HEALTH AND BIOMEDICAL RESEARCH
Hosted by the Immunology IG and NIAID

Cancelled: Louis Ignarro, UCLA (hosted by Reactive Oxygen Species, Clinical Research IG) (Sponsor: Clinical Center)

May 10
Richard Scheller, Ph.D
Department of Molecular and Cellular Physiology
Stanford University Medical Center
MOLECULAR MECHANISMS OF MEMBRANE TRAFFICKING AND EXOCYTOSIS
Hosted by the Neurobiology IG (Sponsor: NIMH)

May 17
NIH Director's Lecture
Cornelia Bargmann, Ph.D.
Vice Chair, Department of Anatomy, UCSF
MECHANISMS OF ODOR DISCRIMINATION IN C. ELEGANS
Hosted by NIDCD

May 24
Doreen Cantrell, Ph.D.
Head, Lymphocyte Activation Laboratory, Imperial Cancer Research Fund, U.K.
SPATIAL AND TEMPORAL ASPECTS OF ANTIGEN RECEPTOR SIGNAL TRANSDUCTION
Hosted by the Immunology IG (Sponsor: NIA)

May 31
Paul Nurse, Ph.D., FRS
Head, Cell Cycle Laboratory, Imperial Cancer Research Fund, U.K.
CONTROLLING THE FISSION YEAST CELL CYCLE
Co-hosted by Yeast Club and Molecular Biology IG (Sponsor: NCI-DBS)

June 7
GM Laureates Lectures

TBA

June 14
Vishva Dixit, M.D.
Director, Molecular Oncology, Genentech Inc.
IDENTIFICATION OF COMPONENTS OF THE CELL DEATH PATHWAY
Co-hosted by Apoptosis, Immunology, and Clinical Research Interest Groups
(Sponsor: NIDCR)

June 21
Alan R. Fersht, Ph.D., FRS
Director, Cambridge Centre for Protein Engineering,
Herchel Smith Professor of Organic Chemistry, Cambridge University, U.K.
STABILITY AND ACTIVITY OF THE TUMOR SUPPRESSOR p53
Hosted by Structural Biology IG (Sponsor: Clinical Center)

June 28
NIH Director's Lecture
Albert Z. Kapikian, M.D.
Head, Epidemiology Section,
Laboratory of Infectious Diseases, NIAID
ETIOLOGY, EPIDEMIOLOGY, AND PREVENTION OF VIRAL GASTROENTERITIS
Hosted by NIAID


**The NIH/FAES is accredited by the Accreditation Council for Continuing Medical Education to sponsor continuing medical education for physicians.

The NIH/FAES designates this educational activity for a maximum of 37 hours in category 1 credit towards the AMA Physician's Recognition Award. Each physician should claim only those hours of credit actually spent in the educational activity.


This page was last updated on MARCH 23, 2000 by Celia Hooper