The 1998-1999 Wednesday Afternoon Lectures
All Lectures are in Masur Auditorium, Bldg. 10, at 3:00 p.m.(exceptions are marked with an * below) CME credits available. The lectures may be accessed from personal computers via NIH's MBONE and are available on videotape at the NIH Library, Bldg. 10, approximately one week after the lecture date. Following the lectures are informal receptions featuring poster displays by winners of the Fellows Awards for Research Excellence (FARE). For further information or special accomodations, please contact: Ms. Hilda Madine

 

September 16: Harvey Lodish , Ph.D.
Whitehead Institute for Biomedical Research
Professor of Biology, MIT
The Erythropoietin Receptor and the Control of Red Cell Proliferation
The NIH Director's Lecture

Hosted by the NIH Fellows Committee and NHLBI

September 23: Charles Sherr, M.D., Ph.D.
Investigator, HHMI, Member and Chair,
Department of Tumor Cell Biology,
St. Jude Children's Research Hospital, Memphis
Integration of Oncogenic Signals by the ARF and p53 Tumor Suppressors
The NIH Director's Lecture

Hosted by the NIH Fellows and NHGRI

September 30: No lecture

October 7: RESEARCH FESTIVAL: No Lecture

October 14: Stanley B. Prusiner, M.D.
Professor of Neurology and Biochemistry
University of California School of Medicine, San Francisco
Prion Biology and Diseases:
A Saga of Skeptical Scientists, Mad Cows, and Laughing Cannibals
The Florence Mahoney Lecture

Hosted by NIA

Special Thursday Lecture
October 15: J. Bruce Beckwith, M.D.
Professor and Head, Division of Pediatric Pathology
Loma Linda University School of Medicine and
Director, National Wilms Tumor Study Pathology Center
The Link Between Teratogenesis and Carcinogenesis:
Lessons from the Wilms Tumor Model
The First Astute Clinician's Lecture
Hosted by The NIH Clinical Center

October 21: Susan Lindquist, Ph.D.
Professor, Department of Molecular Genetics and Cell Biology,
and Investigator, HHMI, University of Chicago
Mad Cows Meet Psi-Chotic Yeast: The Expansion of the Prion Hypothesis
The DeWitt Stetten, Jr. Lecture

Hosted by NIGMS

*Special Monday Lecture
October 26: :Leon E. Rosenberg, M.D.
Professor, Department of Molecular Biology and the Woodrow Wilson School of Public and International Affairs
Princeton University
President, CEO, Funding First, NJ
The Medical Research Enterprise--Only as Strong as its Clinical Links
Second James A. Shannon Lecture

Hosted by the NIH Alumni Association and Office of the Director

October 28: Peter Mombaerts. , M.D., Ph.D.
Assistant Professor and Head, Laboratory of Vertebrate Developmental Neurogenetics,
The Rockefeller University
Targeting Olfaction
Hosted by the Signal Transduction Interest Group

*Special Thursday Lecture
*Special time: 11:00 a.m.

October 29: Gro Harlem Brundtland, M.D.
Director-General, World Health Organization
The New WHO and Partnerships for the Future
Hosted by the Office of the Director and NCI/DCEG

November 4: Steven Pinker, Ph.D.
Director, McDonnell-Pew Center for Cognitive Neuroscience, MIT
Words and Rules: The Ingredients of Language
TheNIH Director's Cultural Lecture

NIMH hosting.

Special Monday Lecture
November: 9: : James Watson,
President, Cold Spring Harbor Laboratory
From the double helix to the human genome project.
Hans Stetten Museum, NHGRI co-hosting.

November 11: VETERANS DAY:No Lecture

Special Thursday Lecture
November 12: Phil Beachy,
Professor, Department of Molecular Biology and
Genetics, Associate Investigator, HHMI
Johns Hopkins University School of Medicine
Hedgehog Protein Biogenesis and Signaling
Hosted by Cell Biology Interest Group

November 18: Carol Prives,
Professor, Department of Biological Sciences
Columbia University of Physicians and Surgeons
Signaling to the p53 Tumor Suppressor Protein
The NIH Director's Margaret Pittman Lecture
,
NICHD Hosting

November 25: David Eisenberg, D.Phil
DOE-UCLA,
3D Domain Swapping in Forming Normal and Pathological
Protein Aggregates, and Interpreting Genome Sequences
in Terms of 3D Structures

Molecular Modeling hosting; NCBI sponsoring

December 2: Eric Schon, Ph.D.
Professor of Genetics and Development
Department of Neurology, College of Physicians and Surgeons
Columbia University
Molecular Genetics of Human Mitochondrial Disease
Mitochondria Interest Group Hosting

December 9: Inder Verma, Ph.D.
American Cancer Society Professor of Molecular Biology,
Laboratory of Genetics,
The Salk Institute for Biological Studies
Gene Therapy: Problems and Prospects
Gene Therapy Interest Group Hosting;NCI/DBS sponsoring

December 16: Peter Howley, M.D.
George Fabyan Professor of Comparative Pathology
Harvard Medical School
Papillomaviruses, Cancer and Ubiquitination
The George Khoury Lecture

DCEG sponsoring

December 23, 1998, through January 6, 1999: WINTER BREAK: No Lectures

January 13: Roger Y.Tsien,
Professor, Depts. of Pharmacology and Chemistry
and HHMI Investigator,
UCSD
Imaging and Manipulating Protein Interactions
and Gene Expression in Individual Cells

Hosted by Cell Biology IG
FARE Poster Session

Special Thursday Lecture
January 14: Robert D. Goldman,
Stephen W. Ranson Professor and
Chairman, Department of Cell and Molecular Biology,
Northwestern University
Intermediate Filaments: From Cell Shape to DNA Replication
SBIG Hosting; NHLBI sponsoring
FARE Poster Session

January 20: Robert Nussbaum,
Chief, Genetic Disease Research Branch,
NHGRI
The Genetic Approach To Understanding Parkinson's Disease
Mider Lecture
:
NHGRI Hosting
FARE Poster Session

January 27:Alfred Sommer, M.D., MHS.
Dean, Johns Hopkins University School of Hygiene & Public Health
and Professor, Epidemiology, and Ophthalmology,
Johns Hopkins University
Epidemiology in the Cause of Vitamin A: Science to Practice
Gordon Lecture,
Epidemiol. and Clin. Trials IG Hosting;
DCEG sponsoring
FARE Poster Session

Feb. 3: James Smith, Ph.D.
RAND Chair in Labor Markets and Demographic Studies
RAND Poplulation Research Center, Santa Monica, CA
Health and Economic Outcomes of New Immigrants
Behavioral and Social Sciences IG hosting;
Clinical Center sponsoring

Feb 10: Mark S. Ptashne, Ph.D.
Ludwig Professor of Molecular Biology
Sloan-Kettering Inst., NY
Imposing Specificity by Localization:
Mechanism and Evolvability

Genetics IG Hosting
FARE Poster Session

Feb. 17: Linda Buck, Ph.D.
Associate Professor of Neurobiology and
HHMI Associate Investigator
Harvard Medical School
Deconstructing Smell
The NIH Director's Lecture
,
Hosted by The NIH Fellows,
Genetics, NIDCD, Host
FARE Poster Session

Feb 24: Richard Frackowiak, M.D., D.SC, FRCP
Co-chair, Wellcome Department of Cognitive Neurology,
University College, London;
Visual Perception and Attention: Human Studies with Functional Neuroimaging
Integrative Neurosciences hosting, NIMH sponsoring
FARE Poster Session

Mar. 3: Fred Alt,
Harvard Medical School
A Critical Role for DNA End-joining Proteins in
Both Lymphogenesis and Neurogenesis
Hosted by Immunology Interest Group

Mar 10: Lewis Cantley,
Professor of Cell Biology, Harvard Medical School and
Chief, Division of Signal Transduction,
Beth Israel Deaconess Medical Center, Boston
Role of PI3K in Cellular Regulation
Department of Medicine, Beth Israel Hospital
Immunology, Cell Biol, Molec. Biol. Co-Hosting

Mar 17: Stan Falkow,
Professor of Microbiology
Stanford University School of Medicine
Probing the Intracellular Life of Bacteria
Hosted by Lambda Lunch; Molecular Biol Co-Hosting; NIDDK sponsoring

Mar 24: Ueli Aebi,
Director, Maurice Mueller Institute for Microscopic Structural Biology,
Basel, Switzerland
Structural and Functional Dissection of Nucleocytoplamic Transport
Structural Biology Hosting; NHLBI sponsoring

Mar 31: Tim Richmond,
Professor for X-ray Crystallography of Biological Macromolecules
Institute for Molecular Biology and Biophysics,
Zurich, Switzerland
Chromatin Crystallography: the 2.0 Angstrom X-ray Structure
of the Nucleosome Core

Co-hosted by Crystallography and Structural Biology; NIDDK sponsoring

April 7: Leonard Guarente, Ph.D.
Professor of Biology, Massachusetts Insitute of Technology
Molecular Analysis of Aging
Hosted by Yeast Interest Group; Molecular Biol. Co-Hosting. NICHD sponsoring.

Apr 14: Craig B. Thompson, M.D.
Investigator, HHMI; Director, Gwen Knapp
Center for Lupus and Immunology Research
Professor, Departments of Medicine and Molecular Genetics and Cell Biology
University of Chicago;
Keeping Cells Alive: Is Caspase Inhibition Enough?
Apoptosis, Cell Biol. Interest Groups Co-Hosting; NCI/DBS sponsoring

Apr 21: Gail R. Martin, Ph.D.
Vice-Chair, Department of Anatomy
University of California, San Francisco
FGF Gene Function in Vertebrate Gastrulation, Brain, and Limb Development
Genetics Interest Group hosting

April 28: Charles Dinarello, M.D.,
Professor of Medicine, Division of Infectious Disease, UCHSC
The Director's R.E.Dyer Lecture
Anti-Cytokine Therapies for Inflammatory Diseases
Hosted by NIAID

May 5: Walter Willett, M.D., Dr.P.H.
Chair, Department of Nutrition and
Professor of Epidemiology and Nutrition,
Harvard School of Public Health and
Professor of Medicine, Harvard Medical School
Diet and Heart Disease: Have We Misled the Nation? 
The Robert S. Gordon, Jr. Lecture

Clinical Research and Epidemiol. Co-Hosting; DCEG sponsoring

May 12: Lynn Matrisian, Ph.D.
Professor of Cell Biology, Vanderbilt University
School of Medicine
Complex Roles for the Matrix Metalloproteinase
Matrilysin in Tumor Progression
Hosted by the Extracellular Matrix group. NCI/DBS sponsoring.

May 19 Jan-Ake Gustafsson,M.D., Ph.D.
Director, Center for Biotechnology
Karolinska Institutet
New Dimensions in Nuclear Receptor Signalling
co-hosted by Molecular Psychiatry,
Neuro-Immune Interactions and Endocrinology Interest Groups;
NIDDK sponsoring

May 26: Roderick Mackinnon, M.D.
Laboratory of Molecular Neurobiology and
Biophysics, Investigator, HHMI
Rockefeller University.
Molecular Basis of K+ Conduction and Selectivity in Potassium Channels
Hosted by Neurobiology Interest Group. Sponsored by NINDS

June 2:Special Double-Header

*Noon: Amartya K. Sen, Ph.D.
1998 Nobel Laureate in Economics and
Master, Trinity College, Cambridge, UK
Conflicting Principles of Health Evaluation
The NIH Director's Cultural Lecture
Hosted by the Office of the Director, NIH

3:00 p.m.: Edward M. De Robertis, Ph.D
N. Sprague Professor of Molecular Oncology, Dept. of Biological Chemistry,
and Investigator, HHMI, UCLA,
Patterning of the Vertebrate Embryo by Secreted Growth Factor Inhibitors
Developmental Biology IG hosting; NICHD sponsoring.

*Special Monday Lecture:
June 7: Joseph Takahashi,
Walter and Mary E. Glass Professor of Life Sciences, and INvestigator, HHMI
Northwestern University.
Molecular Genetics of Circadian Clocks in Mammals
Hosted by Neurobiology Interest Group; NIMH sponsoring

*June 9: GM Laureates Lectures
1:30 to 3:00 p.m.
Speakers TBA

June 16: Scott D. Emr, Ph.D.
Professor of Cellular & Molecular Medicine and
Investigator, Howard Hughes Medical Institute
University of California School of Medincine, La Jolla
Links Between Cell Signaling, Membrane Trafficking and Tumor Progression
Cell Biology Hosting; NIDR sponsoring

June 23: Barbara Imperiali, Ph.D.
Professor of Chemistry,
California Institute of Technology
Chemistry and Biology of Asparginine-Linked Glycosylation
Hosted by Chemistry Int. Grp.; NEI sponsoring

June 30: Kim Nasmyth, Ph.D, F.R.S.
Director, Research Institute of Molecular Pathology, Vienna, Austria
Separating Sister Chromatids
Co-hosted by Yeast, Molecular Biol.; NIDR sponsoring

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This page last updated on April 5, 1999